anchor protein - ορισμός. Τι είναι το anchor protein
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Τι (ποιος) είναι anchor protein - ορισμός

PROTEINS LOCATED ON THE SURFACE OF THE CELL MEMBRANE THAT ARE COVALENTLY ATTACHED TO LIPIDS EMBEDDED WITHIN THE CELL MEMBRANE
Lipid anchor; Lipid anchored membrane protein; Lipid anchored protein; Lipidation; GPI-anchored protein
  • Lipid membrane with various proteins
  • 240x240px
  • Structure of the glycophosphatidylinositol anchor in the plasma membrane of a eukaryotic cell
  • Isoprene unit
  • 
Myristoylation
  • Palmitoylation
  • Prenylation chains (e.g. [[geranyl pyrophosphate]])

Lipid-anchored protein         
Lipid-anchored proteins (also known as lipid-linked proteins) are proteins located on the surface of the cell membrane that are covalently attached to lipids embedded within the cell membrane. These proteins insert and assume a place in the bilayer structure of the membrane alongside the similar fatty acid tails.
A-kinase-anchoring protein         
GROUP OF STRUCTURALLY DIVERSE PROTEINS
A kinase anchoring protein; A-kinase anchoring protein; AKAP; A-kinase-anchoring proteins
The A-kinase anchoring proteins or A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. At least 20 AKAPs have been cloned.
The Anchor, Bankside         
  • The Anchor
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  • Another view of the pub
PUB IN BANKSIDE, LONDON
The Anchor Bankside; Anchor Bankside
The Anchor is a pub in the London Borough of Southwark. It is in the Bankside locality on the south bank of the River Thames, close to Southwark Cathedral and London Bridge station.

Βικιπαίδεια

Lipid-anchored protein

Lipid-anchored proteins (also known as lipid-linked proteins) are proteins located on the surface of the cell membrane that are covalently attached to lipids embedded within the cell membrane. These proteins insert and assume a place in the bilayer structure of the membrane alongside the similar fatty acid tails. The lipid-anchored protein can be located on either side of the cell membrane. Thus, the lipid serves to anchor the protein to the cell membrane. They are a type of proteolipids.

The lipid groups play a role in protein interaction and can contribute to the function of the protein to which it is attached. Furthermore, the lipid serves as a mediator of membrane associations or as a determinant for specific protein-protein interactions. For example, lipid groups can play an important role in increasing molecular hydrophobicity. This allows for the interaction of proteins with cellular membranes and protein domains. In a dynamic role, lipidation can sequester a protein away from its substrate to inactivate the protein and then activate it by substrate presentation.

Overall, there are three main types of lipid-anchored proteins which include prenylated proteins, fatty acylated proteins and glycosylphosphatidylinositol-linked proteins (GPI). A protein can have multiple lipid groups covalently attached to it, but the site where the lipids bind to the protein depends both on the lipid group and protein.